N144
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N144
Sigma
Nitrendipine
>95%, powder
| Synonym: | 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid ethyl methyl ester |
| CAS Number: | 39562-70-4 |
| Linear Formula: | C18H20N2O6 |
| Molecular Weight: | 360.36 |
| EC Number: | 254-513-1 |
| MDL number: | MFCD00082255 |
| PubChem Substance ID: | 24277857 |
Description
| Biochem/physiol Actions | Ca2+ channel blocker; anti-hypertensive. |
Properties
| assay | >95% |
| form | powder |
| color | yellow to green |
| solubility | methanol: 15 mg/mL |
| DMSO: 17.5 mg/mL | |
| H2O: insoluble | |
| Gene Information | human ... ADORA3(140), CACNG1(786), KCNH1(3756), TTR(7276) |
| rat ... Adora1(29290), Adora2a(25369) |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22 |
| Safety Statements | 36 |
| WGK Germany | 1 |
| RTECS | US5653000 |
References
| reference | Chen, X., et al., Quantitative determination of nitrendipine and its metabolite dehydronitrendipine in human plasma using liquid chromatography-tandem mass spectrometry. Biomed. Chromatogr. 15, 518, (2001) |
| Muntwyler, J., and Follath, F., Calcium channel blockers in treatment of hypertension. Prog. Cardiovasc. Dis. 44, 207, (2001) |
